Aim 2 – Define the cell specific mechanisms of tumor cell- and CAF-derived PAR-1 and uPA/uPAR function in mediating tumor cell proliferation/invasion.
Purdue University is home to a nationally and internationally ranked School of Mechanical Engineering and NCI-designated Purdue Center for Cancer Research. Consistently highly ranked, the School of Mechanical Engineering has been at the forefront of providing the most respected engineering research and education in the world. Seventy-four faculty members are dedicated to educating over 1,800 undergraduate, graduate students and postdocs, and to maintaining and developing world-class research programs. Its signature research areas include Bioengineering, Nanotechnology and Heat/Mass Transfer. Faculty members in Bioengineering and Nanotechnology research areas are actively participated in NCI-designated Purdue Center for Cancer Research. In particular, through the Center’s Drug Delivery and Molecular Sensing Program, innovative engineering and technology solutions are developed for both basic and translational cancer research.
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